04 Intervention and Control
As evident in the COVID-19 pandemic, a substantial challenge in managing epidemics is the duration of the application of non-pharmaceutical interventions (NPIs), especially those that disrupt “normal” societal organization and function such as social distancing. These measures quickly become infeasible as pandemic fatigue builds.
  • As pharmaceutical interventions (PIs) such as vaccines, antiviral, or antimicrobial therapies become available, their gradual deployment, concurrently with a potential weakening of the NPIs, raises organizational challenges; uncertainty about vaccine or antimicrobial efficacy or potential for vaccine waning further complicates the issue, as do potential viral evolutions in response to the use of therapeutic tools. COVID-19 has highlighted the need for novel approaches using a One Health (OH) and the following projects aim to do just that.

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04 Intervention and Control
Advancing agent-based simulation scalability »Advancing agent-based simulation scalability
Evolution of the virus: variants, transmission bottlenecks and fitness »Evolution of the virus: variants, transmission bottlenecks and fitness
Implementation of mobility restrictions »Implementation of mobility restrictions
Mathematical modelling of human response behaviour during pandemics »Mathematical modelling of human response behaviour during pandemics
Vaccination and antimicrobials, from the individual to the population »Vaccination and antimicrobials, from the individual to the population
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Vaccination »Vaccination
Nonpharmaceutical Interventions (NPIs) »Nonpharmaceutical Interventions (NPIs)
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