Re-emergence of H1N1 in 1977
Support for theory of immunity was found in the1977 re-emergence of H1N1.

H1N1  was absent in human populations from 1957 to 1977. H1N1 strains collected in 1957 and 1977 were nearly identical, both antigenically and genetically, and the majority of illness occurred in individuals younger than 20 years, presumably because most older individuals retained H1N1 immunity from the 1950s.

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Controlling Infectious Diseases »Controlling Infectious Diseases
Diseases »Diseases
Influenza »Influenza
Background about Flu »Background about Flu
Natural history of infection of influenza »Natural history of infection of influenza
Recovery from Flu? »Recovery from Flu?
Retain lifelong immunity to closely-related strains »Retain lifelong immunity to closely-related strains
Re-emergence of H1N1 in 1977
Why did H1N1 re-emerge in 1977? »Why did H1N1 re-emerge in 1977?
H1N1 strains collected in 1957 and 1977 were nearly identical »H1N1 strains collected in 1957 and 1977 were nearly identical
Majority of illness occurred in individuals younger than 20 years »Majority of illness occurred in individuals younger than 20 years
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