Alcohol was legal then illegal, and was re-legalized
The illegalilzation of alcohol during the Prohibition, and its subsequent re-legalization when Prohibition ended, suggests that such reversals are possible and that therefore the legalisation of drugs need not be irrevocable.
From a comment by Mike Barskey (12/1/2008 2:11:00 PM GMT):

"The Prohibitiion in the US illegalized alcohol, which is essentially where the US government is today regarding drugs. When the Prohibition ended, alcohol was re-legalized (thanks a lot to jury nullification). Why would the reversal of the current drug prohibitions be "probably irrevocable?"
Immediately related elementsHow this works
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Drug Policy – A global perspective »Drug Policy – A global perspective
Legalisation of drugs »Legalisation of drugs
All illegal drugs should be legalised »All illegal drugs should be legalised
Arguments against legalising all illegal drugs »Arguments against legalising all illegal drugs
Legalisation probably irrevocable »Legalisation probably irrevocable
Alcohol was legal then illegal, and was re-legalized
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