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🔎
Step 6: Immunization
Issue
1
#681756
https://naturalist-party.blogspot.com/2021/07/20.html
https://plandemik.blogspot.com/2021/07/10.html
CONTEXT
(Help)
-
STEP A: Samada pandemik kerana ujikaji fraud RT-PCR / RTK-Ag? »
STEP A: Samada pandemik kerana ujikaji fraud RT-PCR / RTK-Ag?
STEP A: Samada pandemik kerana ujikaji fraud RT-PCR / RTK-Ag?☜Seksyen 2 (1) “jangkitan” ertinya kemasukan agen penyakit berjangkit ke dalam benda bernyawa dan pembiakannya dalam benda bernyawa; Akta 342https://greatgameindia.com/portuguese-court-pcr-tests-unreliable/http://plandemic.naturalistparty.nethttps://debategraph.org/malaysia☜F1CEB7
▲
STEP 1: Repot Polis Pertama »
STEP 1: Repot Polis Pertama
STEP 1: Repot Polis Pertama☜https://naturalist-party.blogspot.com/2021/07/1.htmlhttps://naturalist-party.blogspot.com/2021/07/6.htmlhttp://plandemic.naturalistparty.net/p/a.html☜FFB597
▲
STEP 2: Notis Tuntutan (SOVI) »
STEP 2: Notis Tuntutan (SOVI)
STEP 2: Notis Tuntutan (SOVI)☜https://naturalist-party.blogspot.com/2021/07/2.htmlhttps://naturalist-party.blogspot.com/2021/07/3.htmlhttp://plandemic.naturalistparty.net/p/b.html☜FFB597
▲
STEP 3: Repot Polis Kedua (SOVI) »
STEP 3: Repot Polis Kedua (SOVI)
STEP 3: Repot Polis Kedua (SOVI)☜https://naturalist-party.blogspot.com/2021/07/4.htmlhttp://plandemic.naturalistparty.net/p/c.html☜FFB597
▲
TAWARAN HADIAH RM15,000,000 JUTA! »
TAWARAN HADIAH RM15,000,000 JUTA!
TAWARAN HADIAH RM15,000,000 JUTA!☜WE GUARANTEE: 1,5 million € and 0 kilograms of .999 fine gold (Au) bullion for a virologist who presents scientific proof of the existence of a corona virus!☜6EF6A6
▲
STEP B: Samada KKM mempunyai bukti "JANGKITAN" Seksyen 2 (1) Akta 342? »
STEP B: Samada KKM mempunyai bukti "JANGKITAN" Seksyen 2 (1) Akta 342?
STEP B: Samada KKM mempunyai bukti "JANGKITAN" Seksyen 2 (1) Akta 342?☜Bagaimana urutan genetik virus SARS-CoV-2 boleh ditakrifkan tanpa perlu mengasingkan exosomes dan zarah-zarah lain?https://naturalist-party.blogspot.com/2021/07/12.htmlhttps://naturalist-party.blogspot.com/2021/07/13.htmlhttps://naturalist-party.blogspot.com/2021/07/14.htmlhttps://naturalist-party.blogspot.com/2021/07/21.htmlhttps://naturalist-party.blogspot.com/2021/07/22.html☜FFB597
▲
STEP C: Statement of Virus Isolation (SOVI) »
STEP C: Statement of Virus Isolation (SOVI)
STEP C: Statement of Virus Isolation (SOVI)☜Sekiranya zarah yang didakwa sebagai SARS-CoV-2 belum dimurnikan, jadi BAGAIMANA MUNASABAH KKM/KERAJAAN berupaya mengenal bahawa urutan gen RNA zarah ini tergolong sebagai jenis virus baru yang spesifik membuktikan SARS-CoV-2?https://plandemik.blogspot.com/2021/08/a.htmlhttp://plandemic.naturalistparty.net/p/b.htmlhttps://andrewkaufmanmd.com/sovi/https://drtomcowan.com/sovi☜FFB597
▲
STEP D: Kaedah ujikaji "JANGKITAN" Seksyen 2 (1) Akta 342 »
STEP D: Kaedah ujikaji "JANGKITAN" Seksyen 2 (1) Akta 342
STEP D: Kaedah ujikaji "JANGKITAN" Seksyen 2 (1) Akta 342☜Bagaimana kewujudan virus baru SARS-CoV-2 dibuktikan secara saintifik?Bagaimana virus SARS-CoV-2 boleh ditakrifkan tanpa perlu mengasingkan zarah lain?Bagaimana urutan genetik SARS-CoV-2 ditakrifkan dalam konteks ini?Bagaimanakah RT-PCR atau RTK-Ag berfungsi mengesan urutan genetik SARS-CoV-2 dalam konteks ini?Bilakah boleh disimpulkan penemuan urutan genetik tertentu dalam tubuh adalah benar virus SARS-CoV-2 yang berbeza exosomes/zarah lain?☜FFB597
▲
Documented controlled experiments »
Documented controlled experiments
Documented controlled experiments☜Bagaimana kewujudan virus baru SARS-CoV-2 dibuktikan secara saintifik?☜FFB597
■
Step 6: Immunization
Step 6: Immunization☜https://naturalist-party.blogspot.com/2021/07/20.htmlhttps://plandemik.blogspot.com/2021/07/10.html☜FFB597
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[1]
Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus
Cited by:
E D
9:34 AM 19 August 2021 GMT
URL:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035421
Excerpt / Summary
Abstract
Background
Severe acute respiratory syndrome (SARS) emerged in China in 2002 and spread to other countries before brought under control. Because of a concern for reemergence or a deliberate release of the SARS coronavirus, vaccine development was initiated. Evaluations of an inactivated whole virus vaccine in ferrets and nonhuman primates and a virus-like-particle vaccine in mice induced protection against infection but challenged animals exhibited an immunopathologic-type lung disease.
Design
Four candidate vaccines for humans with or without alum adjuvant were evaluated in a mouse model of SARS, a VLP vaccine, the vaccine given to ferrets and NHP, another whole virus vaccine and an rDNA-produced S protein. Balb/c or C57BL/6 mice were vaccinated IM on day 0 and 28 and sacrificed for serum antibody measurements or challenged with live virus on day 56. On day 58, challenged mice were sacrificed and lungs obtained for virus and histopathology.
Results
All vaccines induced serum neutralizing antibody with increasing dosages and/or alum significantly increasing responses. Significant reductions of SARS-CoV two days after challenge was seen for all vaccines and prior live SARS-CoV. All mice exhibited histopathologic changes in lungs two days after challenge including all animals vaccinated (Balb/C and C57BL/6) or given live virus, influenza vaccine, or PBS suggesting infection occurred in all. Histopathology seen in animals given one of the SARS-CoV vaccines was uniformly a Th2-type immunopathology with prominent eosinophil infiltration, confirmed with special eosinophil stains. The pathologic changes seen in all control groups lacked the eosinophil prominence.
Conclusions
These SARS-CoV vaccines all induced antibody and protection against infection with SARS-CoV. However, challenge of mice given any of the vaccines led to occurrence of Th2-type immunopathology suggesting hypersensitivity to SARS-CoV components was induced. Caution in proceeding to application of a SARS-CoV vaccine in humans is indicated.
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