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Majority of illness occurred in individuals younger than 20 years

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Controlling Infectious Diseases
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Diseases
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Influenza
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Natural history of infection of influenza
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Recovery from Flu?
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Retain lifelong immunity to closely-related strains
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Re-emergence of H1N1 in 1977
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Majority of illness occurred in individuals younger than 20 years
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Most older individuals retained H1N1 immunity from the 1950s
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Why did H1N1 re-emerge in 1977?
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H1N1 strains collected in 1957 and 1977 were nearly identical
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