11 Immune response, immune memory and cross-immunity
This project aims to develop and analyze a suite of models of an immune response to an emergent infectious pathogen incorporating immune memory generated by prior infection by related pathogens.
- Such pre-existing immunity has a large influence on the potential for EID spread. Previous infection by one of the common coronaviruses is expected to reduce susceptibility to SARS-CoV-2, and previous infection by SARS-CoV-2 is known to influence a person's response to vaccination and their susceptibility to emerging variants.
Leads: Jane Heffernan (York University), James Watmough (University of New Brunswick) and Jianhong Wu (York University)
Team Members: Jacque Bélair, Morgan Craig, Jonathan Dushoff, Thomas Hurd, Jude Kong, Sajjad Mohammad, James Ooi, and Lin Wang.
Tags: Immunology