comments

Ian Lewis

Assistant Professor, Alberta Innovates Translational Health Chair in Metabolomics, Department of Biological Sciences, University of Calgary.

  • Infectious diseases account for the majority of deaths in developing countries and are among the ten leading causes of mortality in Alberta. The emergence of diverse drug resistant pathogens has made finding new antimicrobial therapies both a Canadian and global health priority.
  • My laboratory investigates the connection between metabolic adaptation and virulence of human pathogens. The ultimate goal of this research is to develop new diagnostic methods to identify high risk patients and novel antimicrobial therapies to control infections. One of the key challenges my laboratory faces is unraveling the complex host-pathogen metabolic dynamics that occur during infections.
  • To address this challenge, we use state-of-the-art mass spectrometry (MS) and nuclear magnetic resonance (NMR) technology to comprehensively quantify the flow of molecules between pathogens and their hosts.
  • This metabolomics approach is a powerful strategy for connecting metabolic phenomena with specific genes and is essential for understanding the metabolic determinants of virulence.

Research areas

  • Precision infection management (PIM)
  • Metabolic adaptations in Pseudomonas aeruginosa
  • Hemoglobin metabolism in the malaria parasite Plasmodium falciparum
  • New analytical tools for identifying and quantifying metabolites in complex mixtures
RELATED ARTICLESExplain
⌅
EIDM 
⌃
People
■
Ian Lewis
⇤
OMNI – People
⇤
University of Calgary
⇤
Pacific Institute for Mathematical Sciences (PIMS)
⇥
Antimicrobial resistance
⇥
Global health
⇥
Malaria
⇥
Pathogens
⇥
Mortality
□
Aamir Fazil
□
Aijun An
□
Alan Diener
□
Alex Petiquan
□
Alexander Rutherford
□
Alexandra Schmidt
□
Ali Asgary
□
Amy Greer
□
Amy Hurford
□
Ana Julia Amezaga
□
Antoinette Ludwig
□
Ardyn Nordstrom
□
Arne Ruckert
□
Arthur Charpentier
□
Ashleigh Tuite
□
Azadeh Aghaeeyan
□
Beate Sander
□
Ben Ashby
□
Benjamin Bolker
□
Bojan Mohar
□
Bouchra Nasri
□
Brett Wilmer
□
Brian Gaas
□
Bryce Morsky
□
Carl E. James
□
Carly Rozins
□
Caroline Colijn
□
Caroline E Wagner
□
Carolyn Fischer
□
Cedric Chauve
□
Charmaine Dean
□
Cheryl Waldner
□
Christian Leuprecht
□
Christian Muise
□
Christina Davy
□
Christine Soteros
□
Christopher Cotton
□
Christopher McCabe
□
Cindy Feng
□
Colin Daniel
□
Connell McCluskey
□
Cory Neudorf
□
Danica Wolitski
□
Daniel Coombs
□
David A. Stephens
□
David Buckeridge
□
David Champredon
□
David Earn
□
David Fisman
□
David Hall
□
Dean Karlen
□
Derek Bingham
□
Diego Bassani
□
Dionne Aleman
□
Donald Estep
□
Dongmei Chen
□
Doug Manuel
□
Ed Furman
□
Edward Susko
□
Edward Thommes
□
Ellen Rafferty
□
Eric Wasylenko
□
Erica Moodie
□
Erin Kirwin
□
Erin Rees
□
Étienne Racine
□
Evan Mitchell
□
Felicia Magpantay
□
François Arès
□
Frank van der Meer
□
Fred Brauer - In Memoriam
□
Frédéric Tremblay
□
Frithjof Lutscher
□
Gary Van Domselaar
□
Gerry Wright
□
Gias Uddin
□
Grace Yi
□
Hanna Jankowski
□
Hao Wang
□
Harini Kapali
□
Heather Murphy
□
Hélène Carabin
□
Héléne Guérin
□
Herman W Barkema
□
Hongmei Zhu
□
Huaiping Zhu
□
Huw Lloyd-Ellis
□
Iain Moyles
□
Ida Ferrara
□
Irena Papst
□
Isaac Bogoch
□
Jacques Bélair
□
James Colliander
□
James Watmough
□
Jane Heffernan
□
Jane Parmley
□
Jason Brown
□
Javier Sanchez
□
Jean-Christophe Boucher
□
Jean-Michel Lariviere
□
Jeannette Janssen
□
Jean-Paul Soucy
□
Jeff Round
□
Jennafer Mee
□
Jesse Shapiro
□
Jianhong Wu
□
Joan Hu
□
Jo-Anne Relf-Eckstein
□
John Edmunds
□
Jonathan Dushoff
□
Jude Kong
□
Julie Arsenault
□
Julien Arino
□
Junling Ma
□
Justin Remais
□
Juxin Liu
□
Kang-Ling Liao
□
Karin Orsel
□
Karine Chalvet-Monfray
□
Kate Harback
□
Katie Clow
□
Kerry Black
□
Kevin Brown
□
Krishna Thakur
□
Kumar Murty
□
Lam Ho
□
Lancer Stephens
□
Larry Svenson - In Memoriam
□
Laura Cowen
□
Laurel Wheeler
□
Lin Wang
□
Lindsay Crowshoe
□
Lindsay Tedds
□
Lisa Kanary
□
Lloyd T. Elliott
□
Lorian Hardcastle
□
Lota Tamini
□
Luc Vinet
□
Luis Seco
□
M. Ethan MacDonald
□
Madeline Ward
□
Maggie Jones
□
Mahmoud Torabi
□
Man Wah Yeung
□
Manisha Kulkarni
□
Manos Papagelis
□
Manuel Morales
□
Marc Brisson
□
Margaret Haworth-Brockman
□
Marie (Betsy) Varughese
□
Marina Freire-Gormaly
□
Mark Joffe
□
Mark Lewis
□
Mark Loeb
□
Markus Hermann
□
Mathieu Maheu-Giroux
□
Matt Keeling
□
Matthew Betti
□
Matthew MacLeod
□
Mea Wang
□
Michael Chen
□
Michael Donohue
□
Michael Kallos
□
Michael Parkins
□
Michael Wolfson
□
Michael WZ Li
□
Michael Y Li
□
Michele Anholt
□
Mikael Jagan
□
Monica Cojocaru
□
Morgan Craig
□
Nabil Afodjo
□
Nancy Bergeron
□
Natalie Anne Prystajecky
□
Nathaniel Osgood
□
Naveed Zafar Janjua
□
Nick Ogden
□
Nicole Basta
□
Nicole Ricker
□
Patrick Brown
□
Patrick Leighton
□
Patrick Lloyd-Smith
□
Paul Gustafson
□
Paul Tupper
□
Peter Park
□
Pouria Ramazi
□
Prabhat Jha
□
Rafal Kustra
□
Rania Wasfi
□
Rebecca Tyson
□
Renny Doig
□
Rita Isabel Henderson
□
Rob Deardon
□
Robert Brennan
□
Robert Greenhill
□
Rosalie Edwards
□
Russell Greiner
□
Samira Mubareka
□
Sana Naderi
□
Sandrine Moreira
□
Sanjeev Seahra
□
Sara McPhee-Knowles
□
Sarah Otto
□
Sasha van Katwyk
□
Sean Hillier
□
Sean P. Cornelius
□
Seyed Moghadas
□
Shannon Majowicz
□
Sharmistha Mishra
□
Shashi Shahi
□
Shelby Sturrock
□
Sherilee Harper
□
Shokoofeh Nourbakhsh
□
Simon de Montigny
□
Steini Brown
□
Stephanie Portet
□
Steve Guillouzic
□
Steve Walker
□
Suzanne Shoush
□
Svetlana Yanushkevich
□
Swetaprovo Chaudhuri
□
Theodore Kolokolnikov
□
Thomas Hillen
□
Thomas Hurd - In Memoriam
□
Thomas Poder
□
Timothée Poisot
□
Timothy Caulfield
□
Troy Day
□
Tsegaye Gatiso
□
Tyler Williamson
□
Usman Alim
□
Valerie Hongoh
□
Venkata Duvvuri
□
Vic Adamowicz
□
Woldegebriel Assefa Woldegerima
□
Xiaoqiang Zhao
□
Xingfu Zou
□
Xuekui Zhang
□
Zahid Butt
□
Zahra Mohammadi
□
Zhilan Feng
□
Graph of this discussion
Enter the title of your article


Enter a short (max 500 characters) summation of your article
Enter the main body of your article
Lock
+Comments (0)
+Citations (2)
+About
Enter comment

Select article text to quote
welcome text

First name   Last name 

Email

Skip