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Genetic and/or epigenetic predisposition to obesity

Degree to which a person is predisposed by his genetic make-up to develop obesity; degree of indirect inheritance that contributes to obesity susceptibility.

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Foresight – Obesity System Map
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1. Biology
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Genetic and/or epigenetic predisposition to obesity
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Appropriateness of nutrient partitioning
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Appropriateness of maternal body composition
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Reliance on pharma remedies
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Degree of primary appetite control by brain
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Resting metabolic rate
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Level of thermogenesis
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Predisposition to activity
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Non-volitional activity (NEAT)
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Appropriateness of maternal body composition
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Genetic susceptibility to an obesogenic environment
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Conscious control of accumulation
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Appropriateness of maternal body composition
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Appropriateness of nutrient partitioning
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Appropriateness of child growth
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Appropriateness of embryonic & fetal growth
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Degree of optimal GI signalling
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Degree of primary appetite control by brain
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Effort to acquire energy
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Extent of digestion and absorption
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Importance of physical need
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Level of adipocyte metabolism
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Level of available energy
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Level of fat-free mass
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Level of infections
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Level of satiety
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Level of thermogenesis
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Predisposition to activity
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Quality & Quantity of breast feeding
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Reliance on pharma remedies
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Reliance on surgical interventions
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Resting metabolic rate
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Side-effects of medicine / drug use
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Strength of lock-in to accumulate energy
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Tendency to preserve energy
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