DENDRAL
Expert system that analyses and identifies chemical compounds by forming and testing hypotheses from experimental data. Meta-DENDRAL—a sub-component—discovered how to synthesise novel chemical compounds and new rules of chemical analysis.
124
DENDRAL even has a publication to its credit.
B. G. Buchanan, D.H. Smith, W.C. White, R. Gritter, E.A. Feigenbaum, J. Ledergerg, and C. Djerassa, 1976.