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Eliminate use of known toxins if possible

If not, reduce the quantities used to minimum.

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Globally, use far fewer natural resources
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Eliminate use of known toxins if possible
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Effective long-term outcomes over immediate efficiency
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Question all assumptions
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Seek physical reality
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Seek simple, robust processes, not complex ones
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Seek the lowest-resource earth-to-earth life cycles
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Cut the size of all other problems
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