Eliminate use of known toxins if possible

If not, reduce the quantities used to minimum.

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The Compression Institute
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Globally, use far fewer natural resources
Eliminate use of known toxins if possible
Effective long-term outcomes over immediate efficiency
Question all assumptions
Seek physical reality
Seek simple, robust processes, not complex ones
Seek the lowest-resource earth-to-earth life cycles
Cut the size of all other problems
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